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Nutrition in Clinical Practice
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Invited Review: Nutrition Support in Pancreatitis

Shivaprasad Marulendra, MD

Section of Nutrition, Division of Gastroenterology, Virginia Commonwealth University, Medical College of Virginia Hospitals, Richmond

Donald F. Kirby, MD, FACP, FACN, FACG

Section of Nutrition, Division of Gastroenterology, Virginia Commonwealth University, Medical College of Virginia Hospitals, Richmond

Nutrition support in patients with pancreatitis has created a challenge for clinicians. Because the pancreas is normally stimulated by the ingestion of food, particularly fat, patients are often denied oral nutrition. This reduction in the ingestion of food, together with the increased metabolic demands of this disease, often results in a negative energy balance and occasionally undernutrition or malnutrition. This review summarizes the etiologies and methods for staging pancreatitis, the physiology of pancreatic exocrine secretion and the response of the pancreas to different methods of nutrition support. The results of clinical trials, which examine both parenteral and enteral nutrition in animals and humans with this disease, are reviewed. Recommendations for nutrition management of patients with acute and chronic pancreatitis and areas for future research are discussed.

Nutrition in Clinical Practice, Vol. 10, No. 2, 45-53 (1995)
DOI: 10.1177/011542659501000245
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A C J Windsor, S Kanwar, A G K Li, E Barnes, J A Guthrie, J I Spark, F Welsh, P J Guillou, and J V Reynolds
Compared with parenteral nutrition, enteral feeding attenuates the acute phase response and improves disease severity in acute pancreatitis
Gut, March 1, 1998; 42(3): 431 - 435.
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