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Nutrition in Clinical Practice
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Metabolic Occurrences in Total Parenteral Nutrition Patients Managed by a Nutrition Support Team

Elizabeth S. Dodds, PharmD, BCPS

Departments of Pharmacy Duke University Health System, Durham, North Carolina

John D. Murray, MS, RPh, BCNSP

Departments of Pharmacy Duke University Health System, Durham, North Carolina

Katherine M. Trexler, RPh, BCNSP

Departments of Pharmacy Duke University Health System, Durham, North Carolina

John P. Grant, MD, CNSP

Departments of Pharmacy Surgery, Duke University Health System, Durham, North Carolina

Few reports have been published examining the impact of a nutrition support service on avoiding serious metabolic complications in hospitalized patients receiving total parenteral nutrition (TPN). We report a high frequency of metabolic abnormalities, with 33% of patients having at least one laboratory value outside the normal range during their course of TPN. Nonetheless, only 13 abnormalities in 11 patients were associated with adverse clinical symptoms in 2747 courses of TPN over 7 years (0.47%). Data were obtained by retrospective analysis of a prospectively maintained nutrition support team database. This report is offered as a standard of care to be attained.

Nutrition in Clinical Practice, Vol. 16, No. 2, 78-84 (2001)
DOI: 10.1177/088453360101600204
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 Nutr Clin PractHome page
M. Pleva, J. M. Mirtallo, and S. M. Steinberg
Hyperglycemic Events in Non-Intensive Care Unit Patients Receiving Parenteral Nutrition
Nutr Clin Pract, October 1, 2009; 24(5): 626 - 634.
[Abstract] [Full Text] [PDF]