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Systematic reviews and lifelong diseasesSystematic reviews of randomized controlled trials provide an evidence base for treatment but too often fail to give adequate information on long-term outcomes. Elphick and colleagues discuss the limitations of the systematic review of randomized controlled clinical trials for patients with chronic or lifelong diseases and suggest that long-term observational studies have a place in the evaluation of the benefits and risks of treatment.
Nutrition in Clinical Practice, Vol. 18, No. 1,
106 (2003) |
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