Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

Click here for more infromation

Click here to sign up for SAGE Journal Email Alerts today!

Sign In to gain access to subscriptions and/or personal tools.
Nutrition in Clinical Practice
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Mizock, B. A.
Right arrow Articles by DeMichele, S. J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Mizock, B. A.
Right arrow Articles by DeMichele, S. J.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?

Invited Reviews

The Acute Respiratory Distress Syndrome: Role of Nutritional Modulation of Inflammation Through Dietary Lipids

Barry A. Mizock, MD* and Stephen J. DeMichele, PhD{dagger}

* Department of Medicine, Cook County Hospital, Chicago, Illinois; and {dagger} Strategic Research and Development, Ross Products Division, Abbott Laboratories, Columbus, Ohio

Correspondence: Barry A. Mizock, MD, Department of Medicine, Cook County Hospital, 1900 West Polk Street, Chicago, IL 60612. Electronic mail may be sent to bmizock{at}earthlink.net.

The acute respiratory distress syndrome (ARDS) is the most serious form of acute hypoxic respiratory failure. ARDS represents the expression of an acute, diffuse, inflammatory process in the lungs consequent to a variety of infectious and noninfectious conditions. It is characterized pathologically by damage to pulmonary epithelial and endothelial cells, with subsequent alveolar-capillary leak and exudative pulmonary edema. The main clinical features of ARDS include rapid onset of dyspnea, severe defects in gas exchange, and imaging studies demonstrating diffuse pulmonary infiltrates. The role of nutrition in the management of ARDS has traditionally been supportive. Recent research has demonstrated the potential of certain dietary oils (eg, fish oil, borage oil) to modulate pulmonary inflammation, thereby improving lung compliance and oxygenation, and reducing time on mechanical ventilation. This article reviews the alterations in the immune response that underlie ARDS, discusses the physiology of dietary oils as immunonutrients, summarizes animal and human studies that explore the therapeutic effects of dietary oils, and provides clinical recommendations for their use.

Nutrition in Clinical Practice, Vol. 19, No. 6, 563-574 (2004)
DOI: 10.1177/0115426504019006563
Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?


This article has been cited by other articles:


Home page
 JPEN J Parenter Enteral NutrHome page
A. Pontes-Arruda, S. DeMichele, A. Seth, and P. Singer
The Use of an Inflammation-Modulating Diet in Patients With Acute Lung Injury or Acute Respiratory Distress Syndrome: A Meta-Analysis of Outcome Data
JPEN J Parenter Enteral Nutr, November 1, 2008; 32(6): 596 - 605.
[Abstract] [Full Text] [PDF]

Home page
 Nutr Clin PractHome page
S. M. Campbell
An Anthology of Advances in Enteral Tube Feeding Formulations
Nutr Clin Pract, August 1, 2006; 21(4): 411 - 415.
[Abstract] [Full Text] [PDF]

Home page
 Nutr Clin PractHome page
T. W. Rice and J. P. Maloney
Nutrition and Lung Disease
Nutr Clin Pract, December 1, 2004; 19(6): 547 - 549.
[Full Text] [PDF]