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Nutrition in Clinical Practice
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Surrogate Nutrition Markers, Malnutrition, and Adequacy of Nutrition Support

David S. Seres, MD, CNSP

Departments of Medicine and Surgery, Beth Israel Medical Center and Albert Einstein College of Medicine, New York, New Yorka

Correspondence: Correspondence: David S. Seres, MD, CNSP, 170 Second Avenue, Apartment 2D, New York, NY 10003. Electronic mail may be sent to dseres{at}chpnet.org.

Surrogate nutrition markers are used to assess adequacy of nourishment and to define malnutrition despite evidence that fails to link nourishment, surrogate markers, and outcomes. Markers such as serum levels of albumin, prealbumin, transferrin, and IGF-1 and delayed hypersensitivity and total lymphocyte count may be valid to help stratify risk. However, it is not appropriate to consider these as markers of adequacy of nourishment in the sick patient.

Nutrition in Clinical Practice, Vol. 20, No. 3, 308-313 (2005)
DOI: 10.1177/0115426505020003308


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