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Nutrition in Clinical Practice
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Invited Reviews

Clinical Use of Probiotics in the Pediatric Population

Beth Wallace, MD

From the Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.

Correspondence: Address correspondence to: Beth Wallace, Children's Hospital of Philadelphia, Clinical Nutrition, 34th and Civic Center Blvd, Philadelphia, PA 19104; e-mail: wallacee{at}email.chop.edu.

Probiotics are live microorganisms that produce a benefit to the host when provided in adequate amounts from food or supplements. There is an increased interest in the use of probiotics in the management and treatment of complex medical conditions. Recommendations for probiotic supplementation in the pediatric population are often conflicting due to limited research in many pediatric disease states. Research on single and multistrain probiotics has shown promise for some pediatric populations. This review discusses the research available for probiotic supplementation for children with irritable bowel syndrome, Crohn's disease, diarrhea, short bowel syndrome, human immunodeficiency virus, and food allergies. Probiotic safety also is discussed.

Key Words: probiotics • pediatrics • gastrointestinal conditions • diarrhea

Nutrition in Clinical Practice, Vol. 24, No. 1, 50-59 (2009)
DOI: 10.1177/0884533608329298
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A. Minocha
Probiotics for Preventive Health
Nutr Clin Pract, April 1, 2009; 24(2): 227 - 241.
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