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Nutrition in Clinical Practice
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*Compound via MeSH
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*Liver Diseases
*Vitamins
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*SELENIUM COMPOUNDS
*SELENIUM, ELEMENTAL
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Invited Reviews

Pediatric Parenteral Nutrition: Putting the Microscope on Macronutrients and Micronutrients

Julie Slicker, RD, CSP, CD, CNSD
Sarah Vermilyea, RD, CSP, CD, CNSD

From the Children's Hospital of Wisconsin, Milwaukee, Wisconsin.

Correspondence: Address correspondence to: Julie Slicker, RD, CSP, CD, CNSD, Children's Hospital of Wisconsin, MS 802, PO Box 1997, Milwaukee, WI 53201-1997; e-mail: jslicker{at}chw.org.

Parenteral nutrition can be a life-saving therapy, but its benefits need to be balanced with a unique set of risks and complications. Methods of practice vary because there is a dearth of research in the area of pediatric parenteral nutrition. This article reviews the available literature on parenteral nutrition in children and provides suggestions on prevention and management of parenteral nutrition–associated liver disease. Some of the issues discussed in this article include glucose infusion rates, cycling of parenteral nutrition, copper and manganese toxicity, and the provision of glutamine, selenium, and carnitine.

Key Words: cholestasis • trace elements • micronutrients • manganese • copper • selenium • glutamine • liver diseases • parenteral nutrition • parenteral nutrition, total • pediatrics • child • infant

Nutrition in Clinical Practice, Vol. 24, No. 4, 481-486 (2009)
DOI: 10.1177/0884533609339073
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