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Nutrition in Clinical Practice
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Pentobarbital Coma in Neurosurgical Patients: Nutrition Considerations

Barbara Magnuson, PHARMD

Nutrition Support Service, University of Kentuchy Medical Center

Jimmi Hatton, PHARMD, BCNSP

College of Pharmacy, University of Kentuchy Medical Center

Thomas N. Zweng, MD

Department of Surgery, University of Kentucky Medical Center, Lexington

Byron Young, MD

Department of Surgery, University of Kentucky Medical Center, Lexington

Neurosurgical patients in pentobarbital coma are a complex nutrition support population. Physiologic changes associated with the primary injury to the brain, combined with the pharmacodynamic influences of barbiturate therapy, contribute to the difficulties of initiating aggressive nutrition support. Early nutritional repletion is important to the overall outcome of traumatically injured patients. Consequently, factors that influence nutrition support decisions must be understood to assure appropriate intervention. The metabolic changes associated with traumatic head injury, pentobarbital therapy, and nutrition support strategies are reviewed.

Nutrition in Clinical Practice, Vol. 9, No. 4, 146-150 (1994)
DOI: 10.1177/0115426594009004146
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This article has been cited by other articles:


Home page
 Nutr Clin PractHome page
A. M. Cook, A. Peppard, and B. Magnuson
Nutrition Considerations in Traumatic Brain Injury
Nutr Clin Pract, December 1, 2008; 23(6): 608 - 620.
[Abstract] [Full Text] [PDF]

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 The Annals of PharmacotherapyHome page
A. M Stevens, J. E Then, K. M Frock, B. A Crookes, C. Commichau, B. T Marden, B. J Beynnon, and J. A Rebuck
Evaluation of Feeding Intolerance in Patients with Pentobarbital-Induced Coma
Ann. Pharmacother., April 1, 2008; 42(4): 516 - 522.
[Abstract] [Full Text] [PDF]

Home page
 Nutr Clin PractHome page
B. Magnuson, J. Hatton, S. Williams, and T. Loan
Tolerance and Efficacy of Enteral Nutrition for Neurosurgical Patients in Pentobarbital Coma
Nutr Clin Pract, June 1, 1999; 14(3): 131 - 134.
[Abstract] [PDF]