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We often think of inflammation as occurring as a result of an acute injury.
However, we learn in this issue that inflammation is associated with chronic
diseases. The issue begins as Dr Gordon Jensen defines the realm of
inflammation as "an expanding universe" and highlights
implications of nutrition therapy on inflammatory conditions. Next, Dr Collier
and colleagues expound on the link between hyperglycemia and inflammation.
This thorough article reviews mechanisms of stress hyperglycemia,
relationships between inflammation and elevated glucose levels, methods of
glucose control, and outcomes associated with stringent glucose control. In a
similar fashion, Dr Cave et al review, in detail, proposed mechanisms of
obesity-induced inflammation, as well as the role of adipokines and cytokines
in the inflammatory process. The authors then evaluate the potential role of
The next article by Overholser and Sowinski is a follow-up article on biostatistics. Part 1 of this article in the December 2007 issue addressed descriptive statistics; this article focuses on inferential statistics.
There is a trio of unsolicited papers in this issue of NCP.
Keswani, Neven, and Semrad report the results of their investigation to
determine if undiagnosed celiac disease was present in a small cohort of
patients with short bowel syndrome. In the next article, Roberts and Lyman
evaluate rates of microbial contamination in enteral feeding sets used at
home. They conclude that in their population, a majority (77%) of their
patients did not have significant contamination of feeding sets even after 48
hours. Scolapio and colleagues then summarize effective change in knowledge
and practice among attendees of a continuing education course. A book review
by Harper finishes this issue of
NCP.
Nutrition in Clinical Practice, Vol. 23, No. 1,
vi (2008)
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-3 fatty acids, soy protein, leucine, arginine, betaine,
S-adenosylmethionine, carnitine, magnesium, zinc, and
-lipoic acid as
pharmaconutrients. As DeLegge and Smoke discuss, neurodegeneration can also be
considered an inflammatory condition. The authors review data suggesting that
nutrition interventions could potentially reduce inflammation associated with
neurodegeneration. Parenteral nutrition may also cause inflammation. Drs Hise,
Compher, and Brown review the literature with regards to the etiology of
inflammation associated with long-term use of parenteral nutrition. Clark and
Mullin follow with a review on complementary approaches to immunomodulation.
They review the immunodulatory roles of resveratrol, green tea, curcumin,
boswellia, fish oil, vitamin D, and probiotics. Rounding out the themed
articles is a paper by Liepa, Sengupta, and Karsies. They focus on polycystic
ovary syndrome—the etiology, prevalence, and treatment including
proposed nutrition interventions. 